IGF - 1 LR3 Xt Labs USA
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IGF-1 LR3 Xt Labs - Long R3 Insulin-like Growth Factor-1
Product Name: IGF-1 LR3
Manufacturer: XT Labs
Active Substance: Insulin-like Growth Factor-1 Long R3
Concentration: 1 mg (1000 mcg) per vial
What is IGF-1 LR3 and What Does It Do?
IGF-1 LR3 is a synthetic, genetically engineered version of Insulin-like Growth Factor-1 (IGF-1). It is a modified peptide that is significantly more potent and has a longer half-life than natural IGF-1. Natural IGF-1 is a hormone that plays a critical role in muscle growth, cell repair, and metabolism, and its production is stimulated by Growth Hormone (HGH).
The "Long R3" modification means:
Increased Half-Life: It has a half-life of 20-30 hours, compared to just a few minutes for natural IGF-1.
Reduced Protein Binding: It is less likely to bind to proteins in the blood, making it more bioavailable and active.
Its primary mechanisms of action are:
Hyperplasia: It may stimulate the creation of new muscle cells (hyperplasia), in addition to enlarging existing ones (hypertrophy).
Nutrient Shuttling: It promotes the uptake of amino acids and glucose into muscle cells, powerfully shuttling nutrients to the muscles.
Cell Proliferation & Differentiation: It stimulates the growth and development of various cell types, including muscle and satellite cells.
Purpose in Bodybuilding and Performance Enhancement
IGF-1 LR3 is considered one of the most powerful peptides for bodybuilding, used for its profound effects on muscle growth and recovery.
Quality Muscle Growth: It promotes lean, high-quality muscle gains. The growth is often described as adding "mature" muscle density rather than watery mass.
Site Enhancement (Spot Reduction/Fat Loss): A common practice is localized, subcutaneous injection into a specific muscle group (e.g., biceps, calves, pectorals). This is believed to promote growth and fat loss specifically in that area, though systemic effects are also significant.
Enhanced Recovery: It dramatically speeds up recovery from intense training by promoting the repair of muscle tissue and reducing soreness.
Fat Loss: It can enhance metabolic rate and promote lipolysis (fat breakdown).
Synergy with HGH: It is often used in conjunction with Growth Hormone to amplify the effects of both compounds, as IGF-1 is a primary mediator of HGH's anabolic actions.
Dosage, Administration, and Reconstitution
Important: IGF-1 LR3 is supplied as a lyophilized (freeze-dried) powder that must be reconstituted with Bacteriostatic Water or Acetic Acid before use. It is administered via subcutaneous (SubQ) injection.
Reconstitution: Add the liquid to the peptide vial, gently swirling until the powder is fully dissolved. Once reconstituted, it must be refrigerated.
Common Protocol:
Dosage: A common and effective dosage ranges from 20 mcg to 60 mcg per day. Many users start at 20-30 mcg to assess tolerance.
Cycle Length: Cycles are typically short, lasting 4 to 6 weeks, followed by an equal period off to prevent receptor desensitization.
Timing: It is typically injected post-workout on training days to maximize nutrient shuttling to the trained muscles. On non-training days, it can be injected in the morning.
Site Injection: For localized effects, it is injected SubQ into the fatty tissue overlying the muscle group trained. For systemic effects, abdominal SubQ injections are common.
Benefits and Effects
Promotes significant, quality lean muscle gains.
Dramatically enhances recovery and reduces muscle soreness.
Increases muscle fullness and vascularity.
Can promote localized fat loss when used for site enhancement.
Potentiates the effects of Growth Hormone.
Potential Side Effects and Warnings
IGF-1 LR3 is a very powerful compound and carries significant risks, especially at higher doses.
Hypoglycemia: This is the most common and serious risk. As a potent insulin-like compound, it can drastically lower blood sugar levels, leading to dizziness, shaking, sweating, and fainting. It is crucial to consume a carbohydrate-rich meal/snack around the time of injection.
Organ Growth: Since IGF-1 promotes the growth of all cells, there is a theoretical risk of internal organ enlargement (splanchnomegaly), particularly with long-term, high-dose use.
Numbness and Tingling: Some users report tingling in the hands (carpal tunnel-like symptoms) due to fluid retention.
Headaches and Lethargy: Common side effects, often related to blood sugar fluctuations.
Acromegaly Symptoms: Long-term abuse could potentially lead to the growth of bony tissues in the face, hands, and feet.
Increased Cancer Risk: As IGF-1 is a potent growth factor, there is a serious theoretical concern that it could accelerate the growth of pre-existing, undiagnosed tumors.